Samuel Eto’o is out of Chelsea’s clash with Southampton on Sunday afternoon after picking up a groin injury in Tuesday evening’s Champions League defeat to Basel.
The Cameroon international, who is set to miss the next two weeks, could be replaced by Fernando Torres, who returned from his abductor injury midweek.
David Luiz is doubtful as he struggles to shake of a knee injury, while Marco van Ginkel is out for the majority of the season with a knee injury.
Victory could see Jose Mourinho’s men close the gap on leaders Arsenal, depending on their result against Cardiff City on Saturday afternoon.
Meanwhile second place Liverpool, who are level on points with the Blues, travel to Hull City on Sunday afternoon.
Elsewhere, Mourinnho has taken a swipe at Romelu Lukaku, with many still questioning why he was again allowed to go out on loan this season, the Mail Online understands.
Following a successful season-long stint at West Bromwich Albion last year, the Belgium international moved to Everton for the season on transfer deadline day.
With Chelsea’s current set of forwards largely misfiring, journalists and fans alike have been rueing the clubs decision to temporarily part company with the 20 year old, but the Blues boss has said it is for the player to reveal the reason why.